The srcset with the sizes attribute is definitely the way to go to create responsive, flexibel, adaptive images.

Unfortunately there is no way to tell the browser, that a specific image doesn't gain much perceived quality with a higher density or that image quality of a specific image isn't important for the user experience.

Due to the fact, that a 2x retina means 4x data and 3x retina means 9x data, performance can suffer even on good connections badly.

lazySizes data-optimumx feature (build on top of data-sizes="auto") gives the developer more control to use adaptive images markup, but opt-out from to high retina at some point by defining the optimum density.